Mechanochemical synthesis of tetramic acids and their biomimetic ring expansion to 4-hydroxy-2-pyridones

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Green Chem., 2025, Advance Article
DOI: 10.1039/D5GC03085D, Communication
Open Access Open Access
Creative Commons Licence&nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Kalliopi Mazaraki, Aimilia Eirini Tsirozidou, Basil Kakarikas, Alexandros L. Zografos
Rolling towards pyridones: ball milling enables green tetramic acid synthesis and its smooth biomimetic expansion to valuable heterocycles.
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