Episomal plasmid engineering and pathway optimization for efficient 1,8-cineole production in Yarrowia lipolytica

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Green Chem., 2026, Advance Article
DOI: 10.1039/D5GC04873G, Paper
Chenxi Li, Qinghua Yang, Zikang Huang, Qiaomin Yang, Wenjin He, Jianzhong Huang, Feng Qi
An efficient CEN1 variant-derived episomal plasmid system accelerated gene expression markedly beyond genomic integration, enabling a robust Y. lipolytica platform for high-titer 1,8-cineole production.
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