Co-immobilization of enzymes and cofactors enabled by liquid–liquid phase separation for continuous-flow catalysis

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Green Chem., 2026, Advance Article
DOI: 10.1039/D6GC00150E, Communication
Chuyi Xiao, Zhiyong Luo, Yuyao Wan, Kaihui Xu, Xingyuan Fang, Dingyi Yang, Ting Guo, Hao Yuan, Tao Meng
A carrier-free continuous-flow catalytic system based on LLPS co-immobilizes enzymes and cofactors in an all-aqueous environment, enabling self-sufficient biocatalysis with excellent activity and stability.
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