Copper-catalyzed amidoalkylation of amines via C–C bond cleavage from cyclic oxaziridines

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Green Chem., 2025, Advance Article
DOI: 10.1039/D5GC03001C, Communication
Xin-Xin Liu, Shaohong Wang, Yuan Zhang, Fan Yang, Hong-Jie Miao, Peng-Chen Ma, Li-Na Guo, Pin Gao
We have successfully established an efficient copper-catalyzed C–C bond cleavage of cyclic oxaziridines and the C(sp3)-N coupling reaction with amines under mild and redox neutral conditions with 100% atom-economy.
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