De novo biosynthesis of the 4,6-dihydroxycoumarin in Escherichia coli

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Green Chem., 2024, Accepted Manuscript
DOI: 10.1039/D4GC05694A, Paper
Open Access Open Access
Qi Gan, Tian Jiang, Chenyi Li, Xinyu Gong, Jianli Zhang, Bhaven Desai, Yajun Yan
Coumarins and their derivatives possess crucial biochemical and pharmaceutical properties. However, the exploration of the coumarin biosynthesis pathways remains limited, restricting their microbial biosynthesis, especially for hydroxycoumarins. In this work,…
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