Dynamic kinetic resolution of tert-alcohols via combination of a lipase/Brønsted acid in a biphasic reaction medium

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Green Chem., 2025, Advance Article
DOI: 10.1039/D4GC06535B, Paper
Takusho Kin, Satoshi Horino, Jihoon Moon, Momoka Tsuda, Harald Gröger, Shuji Akai, Kyohei Kanomata
A green process for the synthesis of optically active tert-alcohols has been developed by combining lipase- and H2SO4-catalysed reactions in a biphasic recycling flow system.
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