eSpiro: A scalable and sustainable electrosynthetic route to spiroketals via anodic oxidation of malonic acids

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Green Chem., 2025, Advance Article
DOI: 10.1039/D5GC01767J, Communication
Marylise Triacca, Carl D. Reens, Hamish Stephen, Kevin Lam
Metal-free, electrochemical synthesis of spiroketals is presented, using anodic oxidation of malonic acids under mild conditions. This sustainable approach enables access to diverse spiroketal frameworks with potential for flow adaptation.
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