Green synthesis of building blocks, drug candidates and fine chemicals by barochemistry: application of high pressure in organic synthesis

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Green Chem., 2025, Advance Article
DOI: 10.1039/D5GC01075F, Tutorial Review
Open Access Open Access
Guoshu Xie, Valerie Wright, Alexander Lazarev, Gary Smejkal, Vera Gross, Béla Török
Barochemistry, the use of high hydrostatic pressure, is a powerful green activation method that enables effective, scalable, energy efficient and solvent-free synthesis—offering a distinct advantages over other non-traditional activation techniques.
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