Innovative mechanochemical synthesis of lipopeptide surfactants through direct amidation of fatty esters: application to silk-derived amphiphilic lipopeptides

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Green Chem., 2026, Advance Article
DOI: 10.1039/D5GC06742A, Paper
Open Access Open Access
Lara Wehbe, Erwann Guénin, Alla Nesterenko
New mechanochemical strategy for producing lipoamino acids through amidation was studied. The methodology was applied to produce amphiphilic silk sericin lipopeptides.
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