Interfacial molecular engineering-driven self-emulsification: a green strategy for surfactant-free, high-efficiency oral delivery of cyclosporine A

Green Chem., 2025, Advance Article
DOI: 10.1039/D5GC02056E, Paper

Peiya Shen, Enshi Hu, Jitong Shi, Ruipeng Li, Xingyu Zhu, Yuan Gao, Jianjun Zhang, Yuanfeng Wei, Shuai Qian
A green chemistry strategy for oral peptide delivery using biodegradable cellulose and food-grade trans-anethole enables solvent-free self-emulsification, enhancing bioavailability while minimizing environmental impact and energy use.
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