Recovery and reuse of homogeneous palladium catalysts via organic solvent nanofiltration: application in the synthesis of AZD4625

Green Chem., 2025, Advance Article
DOI: 10.1039/D4GC06334A, Paper

Open Access

&nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Hui Xiao, William R. F. Goundry, Rhys Griffiths, Yanyue Feng, Staffan Karlsson
Using OSN, a homogeneous Pd catalyst in AZD4625 synthesis is separated and reused for five cycles, maintaining over 90% conversion.
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