Sailing the stormy seas of sustainability: flow vs. batch in API synthesis

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Green Chem., 2026, Advance Article
DOI: 10.1039/D6GC01852A, Critical Review
Open Access Open Access
Francesco Ferlin, Federica Valentini, Filippo Campana, Xing Wei, Luigi Vaccaro
Herein is reported a quantitative comparison between batch and flow protocols for the sustainable synthesis of APIs, focusing on mass-related green metrics, solvent safety and hazards, and space-time-yield. Image partly generated by Google Gemini tool.
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