Site-selective electrochemical C(sp3)–H late-stage functionalization of pyrazolones

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Green Chem., 2025, Advance Article
DOI: 10.1039/D5GC02947C, Communication
Jing-Yi Zhang, Ming-Han Li, Yu-Shun Cui, Ying Yang, Miao Lai, Zi-Xun Gao, Lin-Yu Zheng, Si-Ao Lu, Bin-Tao Liu, Fang-Ling Lu, Yu-Lin Feng
A cost-effective and sustainable electrochemical strategy enables highly selective C(sp3)–H functionalization of pyrazolones. 116 valuable novel pyrazolone derivatives were rapidly synthesized under mild conditions.
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