Solid-state aromatic nucleophilic fluorination: a rapid, practical, and environmentally friendly route to N-heteroaryl fluorides

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Green Chem., 2025, Advance Article
DOI: 10.1039/D4GC06362G, Paper
Open Access Open Access
Koji Kubota, Tetsu Makino, Keisuke Kondo, Tamae Seo, Mingoo Jin, Hajime Ito
A simple mechanochemical protocol for solid-state aromatic nucleophilic fluorination using potassium fluoride (KF) and quaternary ammonium salts was developed.
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