Sustainable bioproduction of triterpenoid sapogenins and meroterpenoids in a metabolically engineered medicinal mushroom

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Green Chem., 2025, Advance Article
DOI: 10.1039/D4GC06275B, Paper
Fidelis Azi, Xiaomei Dai, Yuxiang Hong, Liqing Yin, Mingsheng Dong, Peng Xu
Metabolic engineering of a medicinal mushroom for sustainable bioproduction of oleanolic and ursolic acids and meroterpenoids. Oleanolic and ursolic acid production was enhanced by reconstructing the terpenoid backbone biosynthetic pathway.
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