Sustainable photoelectrochemical activation of acetonitrile via transient alkynylnitrile intermediates

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Green Chem., 2026, Advance Article
DOI: 10.1039/D6GC01583B, Paper
Hung-Li Li, Kung-Jui Ho, Pei-Chi Kuo, Ci-Yang Sun, Hung-Chi Chen, Ting-Jun Lin, Yu-Lin Hung, Chien-Wei Chiang
A photoelectrochemical strategy enables de-ammoniative activation of acetonitrile, generating a transient alkynylnitrile intermediate that can be intercepted by amines, amino acids, and peptides.
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