Trimethylsulfoxonium iodide: a green methylating agent for site-selective methylation of carbohydrates

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Green Chem., 2025, Advance Article
DOI: 10.1039/D4GC05327C, Communication
Xiaorui Zhang, Jie Zhao, Qichang Yang, Zhangxuan Chen, Haifeng Wang, Shuang-Xi Gu, Jian Lv
It was reported that trimethylsulfonium iodide [(CH3)3S(O)I], utilized as an eco-friendly and efficient methylating agent for carbohydrates, achieved moderate to excellent yields and site selectivity when combined with an iron catalytic system.
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