Visible-light-induced selenium-mediated cascade cyclization of 2-isocyanobenzonitriles with secondary amines to access indole-fused polycyclics

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Green Chem., 2025, Advance Article
DOI: 10.1039/D5GC01245G, Paper
Dongping Xu, Lizhen Jin, Mengya Huang, Wu Zhang
Controllable synthesis of indolo[2,3-b]quinoxalines and imidazo[4,5-b]indoles was achieved through the cascade cyclization of 2-isocyanobenzonitriles with secondary amines. An intramolecular EDA complex triggered this photochemical radical process.
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