Green Chem., 2025, Advance Article
DOI: 10.1039/D4GC05972G, Communication
DOI: 10.1039/D4GC05972G, Communication
Jiemin Wang, Xueyan Yang, Cheng Peng, Mengyao Pei, Xiaofeng Wei
We present the first catalyst-free fluorination of unactivated tertiary alkyl halides via ball milling. This method offers short reaction times, minimal solvent usage, and is applicable to the synthesis of key intermediates for ledipasvir.
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We present the first catalyst-free fluorination of unactivated tertiary alkyl halides via ball milling. This method offers short reaction times, minimal solvent usage, and is applicable to the synthesis of key intermediates for ledipasvir.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry
