Biomimicry of CO2 transfer through a biotin-mediated ATP-free pathway

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Green Chem., 2025, Advance Article
DOI: 10.1039/D5GC02628H, Paper
Abdussalam K. Qaroush, Feda’a M. Al-Qaisi, Ala’a F. Eftaiha, Rana T. Abu-Saileek, Khaleel I. Assaf, Alex MacDonald, Philip G. Jessop
The Mukaiyama-carbonic acid (MCA) adduct enables CO2 transfer to sodium pyruvate under mild conditions, offering a promising in vitro route for biotin carboxylation.
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