Modular synthetic routes to biologically active indoles from lignin

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Green Chem., 2025, Advance Article
DOI: 10.1039/D5GC01003A, Communication
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Creative Commons Licence&nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Antonio A. Castillo-Garcia, Jörg Haupenthal, Anna K. H. Hirsch, Katalin Barta
Modular functionalization of a lignin-derived C2-acetal enables the synthesis of bio-based indoles via the formation of ortho-amino acetal derivatives and the in situ Schiff-base formation/intramolecular cyclization under mild reaction conditions.
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