Unlocking enhanced reactivity of hexafluoroisopropanol: a sustainable atom economical approach to selective cascade di-π-functionalization of allenamides

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Green Chem., 2025, Advance Article
DOI: 10.1039/D5GC01273B, Paper
Yafia Kousin Mirza, Partha Sarathi Bera, R. Nandini, Dhrubajyoti Talukdar, Sachin Balaso Mohite, Manoj V. Mane, Milan Bera
Hexafluoroisopropanol mediated di-π-functionalization of allenamides with 4-hydroxycoumarin was developed. This strategy features a general cascade C–C and C–O bond formation process for accessing novel pyranocoumarins.
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